The text is organized into 24 chapters. Chapter 1: Introduction, briefly describes the evolution of medicine and surgery at global and national levels. Photographs of historical persons, whose names are remembered, are included in this chapter. The history of Medical-Surgical Nursing, role of nurses and the significance of medical-surgical specialty have been added. This is a unique feature of this book. Chapter 2: Pathophysiological mechanism of diseases explained briefly. Figures and illustrations are included to support the content. Chapter 3: Altered immune response, content covers normal immune system, types of immune reaction and their management. Chapter 4: Fluid electrolyte and acid-base balance. Contents have been presented in a simple manner with illustrations, figures and comparative charts for better comprehension. Chapter 5: Covers operation theater techniques. Chapter 6: Deals with management of patient undergoing surgery. This chapter covers the perioperative nursing care, types of anesthesia, classification of anesthesia drugs and the role of the members of the surgical team. Chapters 7?10: Cover the system wise disorders. Etiology, pathophysiology, clinical manifestations, medical-surgical management and nursing management based on nursing process approach. Advanced diagnostic measures and nursing procedures related to each system have been explained in this chapters. Also highlights important days associated with certain disease conditions. Chapter 11: Collagen disease and connective tissue disorders are included in this chapter. Chapter 12: Nursing management of the elderly. Covers the aging process, home and institutional care are included. Chapters 13?20: Medical-surgical specialties like CVS, Oncology, Breast disorders, Integumentary, ENT, Ophthalmology and Musculoskeletal disorders. Etiology, pathophysiology, clinical manifestations, medical-surgical management and nursing management based on nursing process approach. Advanced diagnostic measures and nursing procedures related to each system have been explained in these chapters. Also highlights important days associated with certain disease conditions Chapter 21: Covers recent trends in the management of STD and AIDS. Chapter 22: Communicable diseases, covers the causative organism, mode of spread, control and precautions and nursing care of all the diseases. The magnitude of the problem, the national control measures are also included. Chapter 23: Emergency management. Chapter 24: Emergency and disaster nursing. Latest disaster management methods are covered.